PAN-CANCER ANALYSIS OF PRE-DIAGNOSTIC BLOOD METABOLITE CONCENTRATIONS IN THE EUROPEAN PROSPECTIVE INVESTIGATION INTO CANCER AND NUTRITION

Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition

Abstract Background Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately.Here, we designed a multivariate pan-cancer analysis to identify metabolites potentially associated with multiple cancer types, while also allowing the investigation of cancer type-specific assoc

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Management of Neglected Medial Peritalar Dislocations: A Preliminary Report with Clinical and Radiological Analysis of 10 Cases

Aim and objective: To study the functional outcome of neglected medial peritalar Construction Vehicles dislocations treated with open reduction and k-wire fixation and assess the clinical and radiological outcome of these neglected cases.Materials and methods: A prospective study was performed on 10 patients between June 2016 and July 2020.All the

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Selection-Mutation Dynamics of Signaling Games

We study the structure of the rest points of signaling games and their dynamic behavior under selection-mutation dynamics by taking the case Gun Cleaning Mats of three signals as our canonical example.Many rest points of the replicator dynamics of signaling games are not isolated and, therefore, not robust under perturbations.However, some of them

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